Abstract

Oscillations, having indispensible roles in the dynamics of various cellular and subcellular processes, are ubiquitous in biological systems. Construction of novel genetic oscillators is one of the key aspects of synthetic biology research. In this chapter, we have examined the underlying design principles of a variety of synthetic oscillators. We have first reviewed the oscillations in natural systems and then specified the basic characteristics of genetic oscillators. Computational methods used for the in silico studies of biological oscillators are described, and a list of software and tools being used is given. We have further discussed about the ten synthetic oscillators and presented a brief summary of the computational and experimental strategies involved in their realizations. This chapter is concluded by providing the hands-on exercises for numerical simulations of two synthetic oscillators.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.