Design optimization of additively manufactured titanium lattice structures for biomedical implants

Abstract

A key advantage of additive manufacturing (AM) is that it allows the fabrication of lattice structures for customized biomedical implants with high performance. This paper presents the use of statistical approaches in design optimization of additively manufactured titanium lattice structures for biomedical implants. Design of experiments using response surface and analysis of variance was carried out to study the effect design parameters on the properties of the AM lattice structures such as ultimate compression strength, specific compressive strength, elastic modulus, and porosity. In addition, the lattice dimensions were optimized to fabricate a diamond cellular structure with properties that match human bones. The study found that the length of a diamond-shaped unit cell strut is the most significant design parameter. In particular, the porosity of the unit cell increases as the strut length increases, while it had a significant reverse effect on the specific compressive strength, elastic modulus, and ultimate compression strength. On the other hand, increasing the orientation angle was found to reduce both the specific compressive strength and modulus of elasticity of the lattice structure. An optimized lattice structure with strut diameter of 0.84 mm, length of 3.29 mm, and orientation angle of 47° was shown to have specific compressive strength, elastic modulus, ultimate compression strength, and porosity of 37.8 kN m/kg, 1 GPa, 49.5 MPa, and 85.7%, respectively. A cellular structure with the obtained properties could be effectively applied for trabecular bone replacement surgeries.