Design of Lectin Mimetics

Abstract

A powerful carbohydrate receptor, which can be seen as a “synthetic lectin”, has recently been developed by Davis et al. The meta-terphenyl-based tetracyclic receptor was inspired by carbohydrate-binding proteins, and was designed to provide both polar and apolar contacts to a disaccharide molecule. Image taken from ref. 9 with permission. Copyright 2007, American Association for the Advancement of Science.