Design of Interface Circuit and Biosensor Fabrication using Inkjet Printer for the Detection of Glucose

Abstract

Objectives: The primary objective of this paper is to demonstrate the use of non conventional methods for printing of biosensors and development of appropriate electronic circuits and embedded systems for detection of glucose. Methods/Statistical analysis: Biosensor Fabrication requries clean room and high investment, In this paper, an attempt is made to design and fabricate biosensor using inkjet printer and the printed sensor is interfaced with signal conditioning and processing unit to detect change in the glucose concentration of the solution to be tested. Findings: Biosensors of various configurations have been modeled using online simulator and have been verified for their characteristics and properties based on software simulations. One of the key challenges in biosensor is fabrication process of biosensors.The serpentine and circular structures sensors are fabricatd and interfaced with signal conditioning circuit and controller. The patterns are printed using silvernitrate solution and the sensor is interfaced with wheatstone bridge and signal conditioning units. The sensing is carried out using reference circuit and the Analog-to-Digital Converter (ADC) circuit. Interface circuit and ADC is configured on Programmable System-on-Chip (PSOC) which are interfaced with Liquid Crystal Display (LCD) for display for readings. Application/Improvements: The circular designed biosensor is reliable than the serpentine structure and has more than 40% improvement in sensitivity in glucose detection.