Abstract
Nanoparticles provide ideal platforms for drug delivery. Together with drugs, various probes, such fluorescent probes, could be incorporated in that platform for bioimaging or in situ tracking of the drugs. One important issue for the drug delivery nano-systems is the safety of the nanomaterials, including the incorporated probes. We found that nano-encapsulated fluorescent proteins could serve as an ideal safe and robust fluorescence probes for the in vivo bio-imaging, with whole body distribution and fast clearance from the body. Fluorescent proteins-encapsulated nanoparticles can deliver siRNA into cells and silence-targeted gene effectively, with some siRNA even being delivered into the cell nuclei (Figure 1).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Nanomedicine: Nanotechnology, Biology, and Medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
