Abstract

In this paper, acoustic tweezers which use beam forming performed by a Fresnel zone plate are proposed. The performance has been demonstrated by finite element analysis, including the acoustic intensity, acoustic pressure, acoustic potential energy, gradient force, and particle distribution. The acoustic tweezers use an ultrasound beam produced by a lead zirconate titanate (PZT) transducer operating at 2.4 MHz and 100 Vpeak-to-peak in a water medium. The design of the Fresnel lens (zone plate) is based on air reflection, acoustic impedance matching, and the Fresnel half-wave band (FHWB) theory. This acoustic Fresnel lens can produce gradient force and acoustic potential wells that allow the capture and manipulation of single particles or clusters of particles. Simulation results strongly indicate a good trapping ability, for particles under 150 µm in diameter, in the minimum energy location. This can be useful for cell or microorganism manipulation.

Highlights

  • Contactless micro-particle manipulation in a liquid has drawn considerable interest in many biomedical, biological, and physical applications [1,2,3]

  • The acoustic trapping force of the gradient force is affected by several parameters such as the acoustic wave frequency, acoustic intensity, particle size, and type of acoustic medium

  • The acoustic potential energy is the crucial characteristic for particle trapping, and it can be calculated by using

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Summary

Introduction

Contactless micro-particle manipulation in a liquid has drawn considerable interest in many biomedical, biological, and physical applications [1,2,3]. The long wavelength used by acoustic tweezers can capture a large group of particles at one time. Such a high trapping capacity is essential for certain kinds of practical experiments. Acoustic tweezers manipulate particles using either a standing wave or a single beam. Acoustic tweezers utilized two counter-propagating, focused ultrasound beams to produce a standing wave at 3.5 MHz, which could capture a frog’s egg or a latex particle 270 μm in diameter in water [8]. Ding demonstrated SSAW-based acoustic tweezers that can manipulate particles, cells, or organisms hold it at [12]. Acousticcells, tweezers based on a single beam use tightly focused transducers to capture manipulate particles, or organisms [12].

30 MHz transducer was used to capture
Schematic theacoustic acoustictweezers tweezers with with a Fresnel
Theory
Simulation
Results
Simulated acoustic potential energy regions correspond correspond to
Conclusions
MHz and an input voltage of 100 Vmagnitude
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