Abstract

The scope of this study is to Design of experiment (DOE) for Fluphenazine Hydrochloride 2.5 mg mg table using extra granular material- Magnesium Stearate with novel technology, Fluphenazine HCl is poorly soluble in water and other common vehicles used for the parenteral adm inistration of drugs. Certain organic solvents may at least partially dissolve fluphenazine HCl. However, when a water-miscible organic solvent containing fluphenazine HCl at near its saturation solubility is diluted with aqueous infusion fluid, the drug tends to precipitate or adsorb to internal surfaces of the infusion set. Oral dosage is easy for intake and unit dose form.

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