Abstract

To solve the noise problem of contactless conductivity detection (CCD) system in micro-fluidic electrophoresis chip, solution scheme of CIC and FIR digital cascade filter based on FPGA was presented. By selecting different filter, which includes CIC filter, FIR filter, and CIC and FIR digital cascade filter, microchip electrophoresis chromatographic signal with noise is compared and analyzed. In this paper, under the conditions of satisfying maximum distortionless output contactless conductivity detection chromatographic amplitude of micro-fluidic electrophoresis chip, the optimum parameters of CIC and FIR digital cascade filter were found, and frequency characteristic of the filter was analyzed. The results show CIC and FIR digital cascade filter can more effectively eliminate the noise of microchip electrophoresis chromatographic signal than CIC filter or FIR filter. CIC and FIR digital cascade filter can be meet real time demand for CCD of micro-fluidic electrophoresis chip.

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