Abstract
Wound infection is the main cause of slow healing and complications of skin burns. Wound dressings can temporarily replace the skin to isolate the contamination and can be anti-infective, which is conducive to wound healing. In this study, a chitosan-Poloxamer-apigenin nanogel dressing (CTS-Plo-Api) was constructed using CTS and Plo, as carriers, and Api. In comparison with traditional treatments, the speed of wound healing is improved with the use of CTS-Plo-Api; moreover, it enhances bacteriostatic and anti-infection ability and has certain analgesic effects. Therefore, we demonstrate that CTS-Plo-Api is an exciting new clinical avenue for the treatment of burn patients.
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