Design of a radical translocation step through 1, n (n = 5, 6, 7) hydrogen transfers for incorporation into new radical cascades

Abstract

The scope and limitations in the 1,n (n = 5, 6, 7) hydrogen transfers from homoallyl radicals of type 10 have been delineated. Encouraging results have notably been obtained with a dioxolane on the side chain to promote a 1,6-H transfer and with a TBS ether to promote a 1,5-H transfer.