Abstract
The development of bone substitutes that meet biomechanical requirements remains a significant challenge in biomedical engineering. This study integrates finite element analysis (FEA) and topology optimization to design high-performance bone substitutes optimized for load-bearing applications. Bone geometries were obtained through advanced scanning technologies, and FEA simulations were carried out using Ansys software to refine the designs. Iterative optimization enhanced the load-bearing capacity and biocompatibility while ensuring a lightweight structure. Material selection and microstructural adjustments were made to achieve optimal mechanical and biological performance. The combination of FEA and topology optimization in this research offers advancements in the design of bone substitutes, showing promising results under physiological loads and indicating strong potential for clinical applications.
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