Design, fabrication and testing of gain SPR sensor chip

Abstract

The gain Surface plasmon resonance (SPR) chip can compensate for the SPR loss, which can improve the sensitivity of the SPR analysis system. In this paper, we design an SPR chip that includes a glass substrate, a gain layer, and a metal layer. Wherein the gain layer is a film obtained by adding IR-140 fuel to different concentrations of methylene chloride in which polymethyl methacrylate (PMMA) is dissolved. Then, we prepared a series of chips with a specific gravity of 0.4%, 0.8%, 1.2%, and 1.6% for the IR-140 in the gain dielectric layer. The fitting effect of the 2nd to 11th order polynomial fitting on the SPR curve is studied, and the SPR curve in this paper is processed by the preferred ninth order polynomial fitting. Finally, by studying the relationship between the thickness of the gain layer and the absorption peak generated by the SPR chip, a chip having an IR-140 dye specific gravity of 0.4% is preferred. The gain layer of the gain SPR chip is also expected to be further studied to further increase its sensitivity.