Abstract

The present work has been carried out on polyherbal formulation named as Linkus Syrup. The herbal formulation consists of Glycyrrhiza glabra, Hyssopus officinalis, Piper longum and Alpinia galangal. The Linkus syrup physico-chemical evaluation such as pH, density, identification of polysaccharide, tanning agents, ascorbic acid and shelf life was complied. The TLC and quantitative determination of alkaloid were quantified. Determination of biomarker has been validated for the analysis of vasicine. The study result revealed that Linkus syrup formulation was well standardized at different levels such as physic-chemical consistency and assay of bio marker compound.

Highlights

  • Cough is one of the most common symptoms for which patients seek medical attention from primary care physicians and pulmonologists [1]. These studies were carried out for the design, development and phytochemical evaluation of a poly herbal formulation named as Linkus syrup

  • In this study for medicinal plants component, Glycyrrhiza glabra, Hyssopus officinalis, Piper longum and Alpinia galangal were formulated for the indication of anti-tussive activity

  • The analytical profile of linkus syrup and there in vasicine have been validated to proved that linkus syrup in different batches confirmed the verification

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Summary

Introduction

Cough is one of the most common symptoms for which patients seek medical attention from primary care physicians and pulmonologists [1]. These studies were carried out for the design, development and phytochemical evaluation of a poly herbal formulation named as Linkus syrup. The syrup consists of leaves of Adhatoda vasica used in the treatment of coughs, bronchitis, asthma, common cold, expectorant and antispasmodic (bronchodilator). Onosma bracteatum leaves and stems are used to treat bronchitis and asthma [18] and main phytochemicals present are naphthazarins, naphthoquinones, alkannins and Shikonins [19]

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