Design and preparation of Fe3O4@PVA polymeric magnetic nanocomposite film and surface coating by sulfonic acid via in situ methods and evaluation of its catalytic performance in the synthesis of dihydropyrimidines

Ali Maleki,Jamal Rahimi,Maryam Niksefat,Zoleikha Hajizadeh

doi:10.1186/s13065-019-0538-2

Ali Maleki, Jamal Rahimi + Show 2 more

Open Access

https://doi.org/10.1186/s13065-019-0538-2

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Journal: BMC Chemistry	Publication Date: Feb 4, 2019
Citations: 42	License type: open-access

Affiliation: Iran University of Science and Technology

Abstract

For the first time, the design and preparation of magnetic polyvinyl alcohol (Fe3O4@PVA) nanocomposite film as a novel nanocatalyst was accomplished by in situ precipitation method. To enhance the catalysis activity, the surface modification of this nanocomposite was carried out by sulfonic acid. After the synthesis of this nanocomposite film, Fourier-transform infrared (FT-IR) spectroscopy, energy-dispersive X-ray (EDX) analysis, field-emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM) images, X-ray diffraction (XRD) pattern, N2 adsorption–desorption by Brunauer–Emmett–Teller (BET), thermogravimetric analysis (TGA) and vibrating sample magnetometer (VSM) were utilized to confirm the structure of the nanocomposite. The catalytic activity of Fe3O4@PVA was investigated by the synthesis of dihydropyrimidine derivatives from an aldehyde, ß-ketoester and urea or thiourea. This heterogeneous nanocatalyst can be easily separated by an external magnet and reused for several times without any significant loss of activity. Simple work-up, mild reaction conditions and easily recoverable catalyst are the advantageous of this nanocomposite film.

Highlights

Magnetic nanoparticles (MNPs) have raised awareness due to their potential application in catalytic activity [1, 2]
As it is illustrated in Scheme 1, according to the co-precipitation method, the Fe3O4@Polyvinyl alcohol (PVA) nanoparticles were synthesized under N2 and in presence of PVA, solution of FeCl3.6H2O and FeCl2.4H2O
In summary, we have introduced Fe3O4@PVA-SO3H nanocomposite film prepared by a facile one-step in situ green precipitation method

Summary

Introduction

Magnetic nanoparticles (MNPs) have raised awareness due to their potential application in catalytic activity [1, 2]. We report for the first time the synthesis and characterization of Fe3O4@PVA-SO3H nanocomposite film and investigate the catalytic application of this nanocomposite film synthesis of dihydropyrimidine (DHPM) derivatives. General procedure for the synthesis of DHPMs 4a–w 0.05 g of Fe3O4@PVA-SO3H magnetic nanocatalyst was added into a solution consists of 1.50 mmol of an aromatic aldehyde, 1.50 mmol of a ß–ketoester, and 2.00 mmol of urea or thiourea.

Results

Conclusion