Abstract

Many neurological disorders are characterized by the focal and anatomically definable lesions within the brain parenchyma. Traditional treatment may introduce major trauma in neurosurgery and conventional medical devices can only trace straight trajectories. To overcome these problems, a design and optimization method for a patient-specific concentric tube robot (CTR) satisfying the constraints of anatomy, surgical tasks and follow-the-leader (FTL) deployment is proposed in this paper. CTR is a tentacle like continuum robot that can work inside confined and complex biological chambers with the ability of tracking complex 3D trajectories. It consists of pre-curved superplastic tubes with hollow cavities to accommodate the surgical tools. These merits make the CTR well suitable for minimally invasive surgeries. This paper introduces a design framework that utilizes preoperative MRI data to configure patient-specific CTR for single and multiple tasks with the minimum number of tubes. A constant curvature circular arc model is built to solve the problem of inverse kinematics. Two iterative optimization methods for single and multiple tasks are proposed to optimize the parameters of the CTR. Initial waypoints of the CTR are produced based on the FTL deployment. The waypoints are then refined using a Follow Shape Rapidly-exploring Random Tree algorithm (FSRRT) for cases that the initial configurations of the CTR cannot completely satisfy the FTL deployment. Simulations and experiments are carried out on a human brain model to validate the proposed methods. The parameters of CTR including the entire length, curvature, radius angle, number, diameter, arc length and the waypoints are obtained. The errors of the FTL deployment are found to be within 2.1mm.

Highlights

  • A wide variety of neurological disorders are characterized by focal and anatomically definable lesions within the brain parenchyma

  • Primary contribution of this paper is to propose an effective method to configurate a patient-specific concentric tube robot (CTR) based on neurosurgical tasks, anatomical constraints and FTL deployment with minimum number of tubes

  • The piecewise constant curvatures model is only considered for its predictable kinematic model and clinical significance, which is favourable for FTL deployment

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Summary

Introduction

A wide variety of neurological disorders are characterized by focal and anatomically definable lesions within the brain parenchyma. Such diseases include intracerebral hemorrhage (ICH), brain tumors, stroke, traumatic brain injury, epilepsy, neurodegenerative disorders, and so on. The compartmental or local therapy method is to deliver therapeutic agents directly at or around the desired site [1]. One technique used cannulas or needles to infuse therapeutic agents or auxil-. The associate editor coordinating the review of this manuscript and approving it for publication was Christopher H.

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