Abstract

This research addresses the design and analysis of a highly sensitive reconfigurable surface plasmon resonance (SPR) sensor for the detection of dengue virus. The SPR sensor is designed with successive layers of SF11 prism, Ag, graphene, antimony trisulphide (Sb2S3), and sensing medium. The sensing medium is infiltrated with various normal and dengue infected blood components like plasma, platelets, and hemoglobin. The angular reflectivity is investigated by employing the well-established transfer matrix method. Geometrical parameters like thickness of the Ag layer and number of graphene layer are sensibly optimized to attain high performance. The proposed structure is modelled in COMSOL Multiphysics environment to investigate the electric field intensity near the Sb2S3 and sensing medium interface. It is perceived that by switching the phase of Sb2S3 from amorphous to crystalline, the sensitivity is increased from 124.61°/RIU to 180.76°/RIU, 96.66°/RIU to 225.75°/RIU, and 127.42°/RIU to 216.57°/RIU for plasma, platelet and hemoglobin cell respectively.

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