Design and manufacture of hybrid mesh for hernia treatment

Abstract

The warp knitting method is typically used to create hernia mesh. It can add new qualities to the meshes due to the formation of micro/nanofibers, cell proliferation, biocompatibility, non-adhesion, and drug release properties. Within the purview of this work, warp-knitted mesh (polypropylene) with micro/nanofibers was created. On this constructed mesh structure, silk fibroin/polyurethane/levan/curcumin fibers were produced using the centrifugal jet spinning technique. When SEM images were examined, the average fiber diameter was 932 ± 407 nm, and the pore diameter was 20 µm. The nanofiber warp-knitted fabric was measured to have a bursting strength of 182.9 ± 11 kPa. It was determined that the abdominal wall’s predicted elasticity value of 15.65% horizontally was enough for both men and women. It was determined that the hybrid mesh structure performed better against E.coli bacteria and that the curcumin-infused mesh had an antibacterial effect. It was found that meshes might be employed as hybrid meshes for the treatment of hernias.