Design and Investigation of Junctionless DGTFET for Biological Molecule Recognition

Abstract

This work utilizes the dielectric modulated detection technique within a junctionless tunnel field-effect transistor (JLTFET) to detect various charged and neutral biomolecules. The electrostatic properties of the proposed dielectric modulated junctionless double gate JLTFET (DM-JL DGTFET) are observed and analyzed to determine the biomolecules like uricase (k = 1.54), Glucose oxidase (k = 3.46), APTES (k = 3.57), keratin (k = 8) and gelatin (k = 14) lipid, carbohydrate, nucleic acid (DNA and RNA), and protein, etc. The SiO2 (gate oxide) is etched and a cavity is shaped under the gate electrode in which the analytes are injected and thus the effective dielectric of the gate oxide is modulated. The injected charge or neutral analytes of the various biomolecules in the immobilized states are responsible to change the electrostatic characteristics of the DM-JL DGTFET device by varying the gate capacitance. The drain current, ION/IOFF, subthreshold slope, and sensitivity of the DM-JL DGTFET are estimated to recognize the biomolecules. The DM-DGJLTFET shows noticeable sensitivity outcomes 15.2 × 1011 for the charged biomolecules, especially the positively charged analytes.