Design and Development of Cefpodoxime Proxetil Dry Suspension Using Fenugreek Powder as Natural Suspending Agent

Abstract

Dry suspension refers to commercial dry solutions that must be dispensed with water. The bitter taste has had a significant impact on the development of oral preparations and therapeutic uses for numerous toxic medicines. The majority of patients want to take effective treatments that taste good and are easy to administer. It is also defined as an intimate mixture of dry, finely split medication and excipients that, when mixed with an appropriate vehicle, produces a suspension. Reconstitutable suspension is reconstituted at the time of use and can thus be used as a liquid formulation, avoiding swallowing issues. When drug stability is a critical concern, the reconstituted system is the formulation of choice. A variety of commercial and government remedies are available as dry powder combinations or granules that are meant to be suspended in water or another vehicle before being taken orally. The current study attempted to compare assessment criteria by employing three natural gums as a suspending agent in a cefpodoxime proxetil oral dry suspensions: acacia, Trigonella foenum graecum (Family: Leguminosae) seeds, also known as fenugreek seeds, and xanthan gum.