Abstract
Photolabile protecting groups (PPGs) are invaluable tools for protecting a variety of functionalities and serve as alternatives to protecting groups that need chemical cleavage. PPGs are mainly classified into 3 categories namely, 2-nitrobenzyl type PPGs, coumarin-based PPGs, and benzyl type PPGs which have been designed by Wang and co-workers based on the meta effect and computational study observations. This work describes the design and synthesis of a julolidine-based benzyl type PPG 4 and the analysis of its reaction intermediates. The julolidine PPG 4 is applied for the protection of alcohols as carbonates, amines as carbamates, carboxylic acids as esters, and hydroxamic acid. Analysis of the photolyzed samples by HPLC has also been conducted.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
