Abstract
This study takes advantage of combining two tissue engineering scaffold fabrication techniques, namely melt extrusion-based 3D printing and porogen leaching, to develop multiscale scaffolds, consisting of an interconnected network, in order to address the requirements of the tissue regeneration process. The scaffolds were characterised and the effect of the microporous surface on cell response and microporous structure on drug release were investigated. The results of this study show microporosity and macroporosity can be modified to optimize scaffold properties based on the requirements of a specific application.
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