Abstract
Selecting probable idiopathic normal pressure hydrocephalus (INPH) patients for shunt insertion presents a challenge because of coexisting comorbidities and other conditions that could mimic NPH. The characteristic appearance of DESH (Disproportionately Enlarged Subarachnoid Space Hydrocephalus) on brain imaging has been shown to have a high positive predictive value in identifying shunt responsive INPH patients (SINPHONI trial). However, the negative predictive value of this radiological sign was not clearly demonstrated.
Highlights
Selecting probable idiopathic normal pressure hydrocephalus (INPH) patients for shunt insertion presents a challenge because of coexisting comorbidities and other conditions that could mimic Normal Pressure Hydrocephalus (NPH)
Disproportionately Enlarged Subarachnoid Space Hydrocephalus (DESH) negative normal pressure hydrocephalus: can patients still benefit from shunt insertion?
Shunt responsive INPH patients were identified as those having objective improvement in their walking speed, neuropsychological assessment as well as subjective improvements in gait, continence and memory, one year post operatively
Summary
DESH negative normal pressure hydrocephalus: can patients still benefit from shunt insertion?.
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