Abstract
Desferrioxamine, a new, specific iron chelating agent, was used in the successful treatment of a child with acute iron intoxication due to ferrous gluconate. The dosage of desferrioxamine was 92 mg/kg given intravenously on three occasions at 12-hour intervals after an initial oral dose of 5 gm. Prompt improvement in the child's clinical status was accompanied by rapid fall in serum iron concentration to normal levels and excretion of about 25 mg of iron in the urine. Further trials of desferrioxamine in the treatment of acute iron intoxication are warranted on the basis of this experience.
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