Abstract
Epoetin alfa is a human recombinant erythropoietin widely used to treat anemia in patients with chronic kidney disease. Anaphylaxis to epoetin alfa has been described, but desensitization to epoetin alfa in the setting of IgE-mediated reaction has not been reported. We present a case of a hemodialysis patient with anemia associated with chronic kidney disease that developed symptoms of anaphylaxis (generalized pruritus, urticaria, oropharyngeal edema, and hypotension) after administration of epoetin alfa and eventually tolerated desensitization to the medication.
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