Desenlace por COVID-19 en pacientes en hemodiálisis

Abstract

Introduction and objectiveThe SARS-CoV-2 epidemic represents a special risk for patients on hemodialysis (HD) due to their comorbidities and the fact that they often have a more severe case of inflammation with fewer symptoms and a worse evolution and outcome. The aim of this study was to detect the clinical and biochemical characteristics of patients on hemodialysis (HD) who presented a suspicious involvement of COVID-19 (Corona Virus Disease – 2019), their risk factors and specific outcomes. Material and methodsThis is a retrospective, observational case report study in HD patients suspected of having COVID-19. Records pointed to comorbidities, clinical and laboratory tests, quantitative reverse transcription polymerase chain reaction (RT-qPCR) tests for SARS-COV-2 and outcomes. Descriptive statistics and linear and logistic regression analyses were performed. ResultsOf the total number of HD patients (1514), 248 HD patients were suspected to have COVID-19 (106 were positive, 83 were negative and 59 suspected using PCR testing); the median age was 51 years (IR 36-63 years), 54.8% were males, had hypertension (87.5%), with a hemoglobin count of 8.9 g (IR 7.5-10.6 g) and symptoms such as cough, fever and dyspnea (65.7, 64.5 and 53.2%, respectively). The fatality rate in the group of patients with positive RT-qPCR was 29.24%. ConclusionsThe mortality and fatality rate is often high in this population. The age group, sex, and cardio-metabolic comorbidities behave similarly to the rest of the non-renal population. Pre-existing biochemical status does not make a difference in the outcome. The predominant symptomatology was pulmonary in nature.