Abstract
Breast cancer is the most common female cancer in Kerala, South India, with the incidence increasing in the past two decades, also in young women. However, there are limited data regarding the burden of disease, its epidemiology and histopathological characteristics in the state. This desciptive study covered 303 breast cancers evaluated during the period of December 2011 to August 2013 in the Department of Pathology, Government Medical College, Kottayam.The patients were also interviewed regarding selected risk factors. The majority of the cases were 41-60 years of age with a mean at presentation of 53 years. Infiltrating ductal carcinoma was the most common subtype, followed by pure mucinous carcinoma and then lobular carcinoma. Of the cases, 6.6% were nullipara and 52.8% had fewer than or equal to 2 children. Median age at first child birth was 23 years (national value-19.8 years). A significant proportion (15%) had family history of breast cancer. Some 13.5%(41 cases) comprised the young breast cancer group (≤40years) with a mean age at first child birth in them was 27.4 years, 5 being nullipara and 6 having a positive family history. Breast cancer awareness, better availability of screening techniques and identification and targeting high risk groups all help to tackle the increasing load of breast carcinoma. A good proportion of cases comprised the young breast cancer group (under 40). Younger women should thus also be educated about breast carcinoma-risk factors, symptoms and diagnostic techniques to help in early detection and effective approach esto treatment.
Highlights
One in ten of all new cancers diagnosed worldwide each year are carcinomas of the female breast, and it is principle cause of death from cancer among women globally
Younger women should be educated about breast carcinoma-risk factors, symptoms and diagnostic techniques to help in early detection and effective approach esto treatment
In the US, approximately 7% of women with breast cancer are diagnosed before the age of 40 years, and this disease accounts for more than 40% of all cancer in women in this age group (Anders et al, 2009).The incidence of breast cancer in Asia is increasing in young women (Keramatinia, 2014)
Summary
One in ten of all new cancers diagnosed worldwide each year are carcinomas of the female breast, and it is principle cause of death from cancer among women globally. In urban areas of developing countries, breast cancer is the most common cancer in women and due to increase in life expectancy, urbanization, and western lifestyles; the incidence has been rising up in low and middle income countries steadily in the last few years. Though the health indices in Kerala are far advanced in comparison to other states in India, the age adjusted incidence rate for breast cancer for the year 2006 was 30.5 in urban and 19.8 in rural areas (Jayalekshmi et al, 2009). Breast cancer is the most common female cancer in Kerala, South India, with the incidence increasing in the past two decades, in young women. Some 13.5%(41 cases) comprised the young breast cancer group (≤40years) with a mean age at first child birth in them was 27.4 years, 5 being nullipara and 6 having a positive family history. Younger women should be educated about breast carcinoma-risk factors, symptoms and diagnostic techniques to help in early detection and effective approach esto treatment
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