Description of Endometrial Cancer Epidemiology at Sabratha National Cancer Institute, Western Libya: A 3-Year Data Analysis

Abstract

Background: Endometrial cancer is the sixth most common cancer in women worldwide and the most frequent gynecological cancer in developed countries. Endometrial cancer mortality rates are high in low- and middle-income countries. Objectives: The current study aims to provide valuable insights into the epidemiology of endometrial cancer at Sabartha cancer institute over three-years periods, with the goal of identifying trends, risk factors, and potential areas for intervention. Methodology: This study is descriptive study, using data which were collected from the all primary endometrial cancers that were diagnosed or treated in the Sabratha National Cancer Institute,Western Libya. The data were collected by hospital cancer registry from 2020 to 2022. The demographic and clinical features of the patients were abstracted included registration number, age, parity, place of residence, family history, and past medical history. Descriptive statistics in form of percentage with 95% CI was used to explain distribution of cancer cases by study variables. The data was compared using Chi-Square using SPSS Statistics for Windows, Version 26. Results: The results showed that over three years period, 82 confirmed cases of endometrial cancer were registered at Sabratha National Cancer Institute. The average age of cases was 57 years. Analysis of the cases by the age group showed that about 21% of cases were from 46-55years group while over 64% were aged above 50 years. Almost of cases (25%) came from Tripoli while only 6% came from Sabratha which is the place of cancer institute. Analysis of study results by parity showed that both nulliparous women and parous women ( > 6 child) represent almost more than 50% of endometrial cancer cases during study period. Also, analysis of study results by family history of endometrial cancer showed that only 14% of cases had family history of the cancer. Conclusion: It can be concluded that the findings of this 3-year data analysis on endometrial cancer epidemiology provide valuable insights into the trends and patterns of this disease. The study highlights the importance of continued surveillance and research to better understand the risk factors, incidence rates, and outcomes associated with endometrial cancer. This information can help inform public health strategies, early detection efforts, and treatment approaches to improve patient outcomes and reduce the burden of this disease. Further research is needed to explore potential interventions and preventive measures that can address the growing impact of endometrial cancer on global health.