Abstract
Abstract:Introduction: Ventilator-associated pneumonia (VAP) is considered one of the most widespread infections present in the intensive care units. It is associated with increase in hospitalization, ventilation days and mortality. The aim of this study is to determine the incidence, bacteriology, impact and clinical outcome of VAP patients.Methods: Prospective observational non interventional study of VAP cohort, conducted in surgical intensive care unit (ICU), Zagazig University Hospitals over a period of 1 year (June 1, 2016–May 31, 2017). This study was approved by the Institutional Review Board, faculty of medicine, Zagazig University. Informed written consents were taken from first degree relatives.Results: incidence of VAP was 9.94%. 76.5% of those patients were male and 23.5% were female. Gram negative bacteria were the main causative organisms in which klebsiella pneumonia was the predominating one. There was significant increase in ventilation days and length of stay (LOS) in ICU. APACHI II score was also significantly higher in VAP patients. VAP cases ware associated with higher mortality and lower cure rate. Conclusion: VAP is a serious ICU acquired infection with significant impact and required effective preventive action.Keywords: Ventilator-associated pneumonia, bacteriology, outcome.
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