Description of a Rare Case of Nodular Fasciitis of the Apical Aspect of the Upper Buccal Sulcus.

Ana Amélia Souza,Andresa Borges Soares,Eldon Guttenberg Cariri Neto,Vera Cavalcanti De Araújo,Maria Teresa De Seixas Alves,Fabricio Passador-Santos

doi:10.1155/2016/4231683

Ana Amélia Souza, Andresa Borges Soares + Show 4 more

Open Access

https://doi.org/10.1155/2016/4231683

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Abstract

This report describes a rare case of nodular fasciitis (NF) of the oral cavity, discussing the clinical, histological, and immunohistochemical characteristics. Histopathologic diagnosis of this type of lesion can be challenging due to its differential diagnosis, which principally includes sarcoma. The patient presented with a painless, well-defined nodule, reported as increasing in size, located at the apical aspect of the upper left buccal sulcus. Histologically, the lesion revealed spindle cell proliferation arranged in fascicles, while immunohistochemistry demonstrated positivity for smooth muscle actin. Eight months after complete surgical excision, no signs of local recurrence have been observed.

Highlights

Nodular fasciitis (NF) is a benign reactive soft tissue lesion, frequently found in the subcutaneous tissues and muscle fascia, which shows proliferation of myofibroblasts and fibroblasts
A 17-year-old white female presented to a private dental clinic complaining of a painless swelling to the apical aspect of the upper left buccal sulcus, which had increased in size over the preceding seven weeks
The challenge in diagnosis of oral NF comes from the fact that the lesion is rare in the oral cavity, as well as the fact that it has a significant histopathologic differential diagnosis [11]

Summary

Introduction

Nodular fasciitis (NF) is a benign reactive soft tissue lesion, frequently found in the subcutaneous tissues and muscle fascia, which shows proliferation of myofibroblasts and fibroblasts. While NF has been frequently reported at many anatomical sites, namely, the upper extremities, the trunk, head and neck, and, lastly, the lower extremities, it is extremely rare in the oral cavity [1, 2]. The presence of a reciprocal translocation involving chromosome 15 has been recently described, which may categorize this lesion as a true neoplasm [7,8,9]. The present report describes the clinical and histopathologic features of a rare case of nodular fasciitis of the oral cavity

Case Report

Discussion