Abstract
Dermoscopy, with and without visual inspection, for diagnosing melanoma in adults.
Highlights
Melanoma has one of the fastest rising incidence rates of any cancer
Despite the observed limitations in the evidence base, dermoscopy is a valuable tool to support the visual inspection of a suspicious skin lesion for the detection of melanoma and atypical intraepidermal melanocytic variants, in referred populations and in the hands of experienced users
Data to support its use in primary care are limited, it may assist in triaging suspicious lesions for urgent referral when employed by suitably trained clinicians
Summary
Melanoma has one of the fastest rising incidence rates of any cancer. It accounts for a small percentage of skin cancer cases but is responsible for the majority of skin cancer deaths. Melanoma is one of the most aggressive forms of skin cancer, with the potential to metastasise to other parts of the body via the lymphatic system and blood stream. It accounts for a small percentage of skin cancer cases but is responsible for up to 75% of skin cancer deaths (Boring 1994; Cancer Research UK 2017a). Melanoma arises from uncontrolled proliferation of melanocytes - the epidermal cells that produce pigment or melanin It most commonly arises in the skin but can occur in any organ that contains melanocytes, including mucosal surfaces, the back of the eye, and lining around the spinal cord and brain. Melanoma in situ and lentigo maligna are both atypical intraepidermal melanocytic variants
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