Abstract

Unilateral nevoid telangiectasia (UNT) is a benign cutaneous vascular disorder, first described by Blaschko in 1899, characterized by clustered telangiectasias with a reticular appearance, blanching with diascopy, and often following a dermatomal pattern especially in C3 and C4 dermatomes, although there are reported cases without this distribution. The pathogenesis is linked mostly to estrogenic action to release nitric oxide causing capillary relaxation; this theory is supported by the predominance in female teenagers and patients with chronic liver disease presenting with this condition; however, the estrogenic role remains unclear because of the lack of receptors in skin and normal estrogen and progesterone levels in some patients with UNT [1].

Highlights

  • Unilateral nevoid telangiectasia (UNT) is a benign cutaneous vascular disorder, first described by Blaschko in 1899, characterized by clustered telangiectasias with a reticular appearance, blanching with diascopy, and often following a dermatomal pattern especially in C3 and C4 dermatomes, there are reported cases without this distribution

  • The pathogenesis is linked mostly to estrogenic action to release nitric oxide causing capillary relaxation; this theory is supported by the predominance in female teenagers and patients with chronic liver disease presenting with this condition; the estrogenic role remains unclear because of the lack of receptors in skin and normal estrogen and progesterone levels in some patients with UNT [1]

  • A 13-year-old female patient presented with a 16-month history of erythematous reticulated macules (Figure 1), sized from 5 mm to 30 mm, affecting the right mammary region and posterior right arm, which was asymptomatic and appeared a few months after her menarche

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Summary

Introduction

Unilateral nevoid telangiectasia (UNT) is a benign cutaneous vascular disorder, first described by Blaschko in 1899, characterized by clustered telangiectasias with a reticular appearance, blanching with diascopy, and often following a dermatomal pattern especially in C3 and C4 dermatomes, there are reported cases without this distribution. The pathogenesis is linked mostly to estrogenic action to release nitric oxide causing capillary relaxation; this theory is supported by the predominance in female teenagers and patients with chronic liver disease presenting with this condition; the estrogenic role remains unclear because of the lack of receptors in skin and normal estrogen and progesterone levels in some patients with UNT [1].

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