Dermatoscopy in diagnosing maculopapular cutaneous mastocytosis

Mirjana Popadic

doi:10.5937/pramed1604109p

Abstract

The diagnosis of cutaneous mastocytosis is based on the clinical finding of the pigmented macules or papules, positive Darier's sign and a dermal infiltrate composed of mast cells that can be better visualized by the use of special stains (Giemsa or Toluidine blue). Clinical, dermatoscopic and histopathological presentations of new appearing pigmented lesions in a female patient were presented. Dermatoscopic findings of pigment network-like structure combined with parallel pigmented lines and central reddish background in a adult patient with new appearing pigmented lesions should led us to searching for cutaneous mastocytosis.

Highlights

Mastocytosis is a rare disease characterized by proliferation and accumulation of mast cells in various organs, most commonly in the skin.[1]
This dermatoscopic structure is seen in numerous nonmelanocytic lesions such as dermatofibroma, solar lentigo, seborrheic keratosis, accessory nipple, Kaposi’s sarcoma and even in the normal skin. [5,6,7] Skin lesions of mastocytosis represent one more nonmelanocytic lesion that may exhibit a pigment network. [1,3,4,8]
Pigmentation is accentuated in the normal skin folds as longer, brown parallel lines in combination with central reddish background, which can not be seen in epidermal melanocytic nevi

Summary

SUMMARY

The diagnosis of cutaneous mastocytosis is based on the clinical finding of the pigmented macules or papules, positive Darier’s sign and a dermal infiltrate composed of mast cells that can be better visualized by the use of special stains (Giemsa or Toluidine blue). Dermatoscopic and histopathological presentations of new appearing pigmented lesions in a female patient were presented. Dermatoscopic findings of pigment network-like structure combined with parallel pigmented lines and central reddish background in a adult patient with new appearing pigmented lesions should led us to searching for cutaneous mastocytosis

INTRODUCTION

CASE REPORT

CONCLUSION

DERMATOSKOPIJA U DIJAGNOSTICI MAKULOPAPULARNE KUTANE MASTOCITOZE