Abstract
Wegener's disease, also known as Granulomatosis with Polyangiitis (GPA), is a rare autoimmune disorder that affects small- to medium-sized blood vessels, causing inflammation and damage to various organs. The disease commonly involves the respiratory tract, kidneys, and the skin. In terms of dermatological symptoms, patients may develop purpura, which are small red or purple spots on the skin caused by bleeding under the skin, or nodules or ulcers that may be painful or non-painful. These lesions can occur anywhere on the body but are often found on the lower legs. Vascular involvement can lead to necrotizing vasculitis, which can be life-threatening if not treated promptly. Early diagnosis and treatment with immunosuppressive therapy can help manage the symptoms and prevent organ damage.
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