Dermatoglyphics in hypertension: a review

Buddhika Tb Wijerathne,Robert J Meier,Thilini C Agampodi,Suneth B Agampodi

doi:10.1186/s40101-015-0065-3

Abstract

Hypertension is a major contributor to the global burden of disease and mortality. A major medical advancement would be a better means to ascertain which persons are at higher risk for becoming hypertensive beforehand. To that end, there have been a number of studies showing that certain dermatoglyphic markers are associated with hypertension. This association could be explained if the risk toward developing hypertension later on in life is somehow connected with fetal development of dermatoglyphics. It would be highly valuable from a clinical standpoint if this conjecture could be substantiated since dermatoglyphic markers could then be used for screening out individuals who might be at an elevated risk of becoming hypertensive. The aim of this review was to search for and appraise available studies that pertain to the association between hypertension and dermatoglyphics.A systematic literature search conducted using articles from MEDLINE (PubMed), Trip, Cochran, Google scholar, and gray literature until December 2014. Of the 37 relevant publications, 17 were included in the review. The review performed according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement.This review showed a fairly consistent finding of an increased frequency of whorl patterns along with a higher mean total ridge count in digital dermatoglyphic results in hypertensive samples compared to controls. However, it was imperative to discuss several limitations found in the studies that could make this association as yet unsettled.

Highlights

Hypertension is a major contributor to the global burden of disease [1]
Hypertension generally is defined as values ≥140 mmHg systolic blood pressure (SBP) and/or ≥90 mmHg diastolic blood pressure (DBP) [5]
Floris et al [11] had used a control group from another study, and they mentioned that the possibility of hypertension in their controls; this study cannot be included in this review

Summary

Introduction

Hypertension is a major contributor to the global burden of disease [1]. It is a significant cause of global mortality [2]. It is estimated that hypertension leads to 9.4 million deaths each year globally [1]. As of 2008, worldwide, approximately 40 % of adults aged ≥25 years had been hypertensive [3]. It was estimated to have close to one billion people with hypertension globally in 2000 and predicted a rise to 1.56 billion by 2025 [4]. Hypertension generally is defined as values ≥140 mmHg systolic blood pressure (SBP) and/or ≥90 mmHg diastolic blood pressure (DBP) [5]

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Discussion

Conclusion