Abstract
Dermatofibrosarcoma protuberans (DFSP) is a rare tumour of the soft tissue tumor involving the dermis, subcutaneous tissue, and in few cases, muscle and fascia. The tumour typically presents as a slowly growing, firm plaque or nodular on the trunk and extremities of young adults. The etiology of dermatofibrosarcoma protuberans has been attributed to a chromosomal translocation t (17;22)(q22;q13) that results in a fusion protein promoting tumour growth through the overproduction of platelet-derived growth factor (PDGF). Diagnosis is made via skin biopsy. Treatment options include complete surgical excision by performing conventional surgery with wide margins (>3 cm) or Mohs micrographic surgery. These lesions are locally aggressive with high rate of recurrence following surgery but the prognosis is excellent when it is treated effectively. These tumours have intermediate malignant potential.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
