Abstract
Summary Newly-horn colostrum-deprived calves and colostrum-fed calves of 3–7 and 7–14 days old were subjected to intradermal tests with endotoxin preparations from E. coli serotypes 078: K 80(B) and 0115:K?. (RVC58) which are common pathogens of calves, and from E. coli 0138: K81 (B) and S. gallinarum. Dermal reactivity to the endotoxins from the 2 E. coli serotypes commonly pathogenic for calves was in general more marked than that to the other 2 endotoxins. Also, a correlation was observed in colostrum-deprived calves between the dermal reactivity of the calves and their sensitivity to intravenous challenge with endotoxin. These findings are discussed in relation to the possible role of hypersensitivity and anaphylaxis in the pathogenesis of colibacillosis.
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