Abstract
Poromas or poroid tumors are a group of rare, benign cutaneous neoplasms derived from the terminal eccrine or apocrine sweat gland duct. There are four poroma variants with overlapping features: dermal duct tumor (DDT), eccrine poroma, hidroacanthoma simplex, and poroid hidradenoma, of which DDT is the least common. Clinically, the variants have a nonspecific appearance and present as solitary dome-shaped papules, plaques, or nodules. They can be indistinguishable from each other and a multitude of differential diagnoses, necessitating a better understanding of the characteristics that make the diagnosis of poroid neoplasms. However, there remains a paucity of information on these lesions, especially DDTs, given their infrequent occurrence. Herein, we review the literature on DDTs with an emphasis on epidemiology, pathogenesis, clinical features, diagnosis, and management.
Highlights
Acrospiromas are a broad class of benign skin adnexal tumors of acrosyringial differentiation
A group of benign growths derived from cells of the terminal eccrine or apocrine sweat gland duct, known as poromas or poroid tumors, fall within this class [1]
There remains a paucity of information on poromas, especially dermal duct tumors (DDT), given their infrequent occurrence
Summary
Acrospiromas are a broad class of benign skin adnexal tumors of acrosyringial differentiation. A group of benign growths derived from cells of the terminal eccrine or apocrine sweat gland duct, known as poromas or poroid tumors, fall within this class [1]. There are several types of poromas: dermal duct tumors (DDT), eccrine poromas, hidroacanthoma simplex, and poroid hidradenomas [1]. Each is differentiated by histopathological features such as lineage (eccrine/apocrine) and location of the poroid cells in relation to the epidermis [2]. It is estimated that sweat gland tumors account for approximately 1% of all primary skin lesion cases, of which eccrine and apocrine poromas are believed to account for approximately 10% [3]. There remains a paucity of information on poromas, especially DDTs, given their infrequent occurrence
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