Abstract

The spatial dynamics of epidemics are fundamentally affected by patterns of human mobility. Mobile phone call detail records (CDRs) are a rich source of mobility data, and allow semi-mechanistic models of movement to be parameterised even for resource-poor settings. While the gravity model typically reproduces human movement reasonably well at the administrative level spatial scale, past studies suggest that parameter estimates vary with the level of spatial discretisation at which models are fitted. Given that privacy concerns usually preclude public release of very fine-scale movement data, such variation would be problematic for individual-based simulations of epidemic spread parametrised at a fine spatial scale. We therefore present new methods to fit fine-scale mathematical mobility models (here we implement variants of the gravity and radiation models) to spatially aggregated movement data and investigate how model parameter estimates vary with spatial resolution. We use gridded population data at 1km resolution to derive population counts at different spatial scales (down to ∼ 5km grids) and implement mobility models at each scale. Parameters are estimated from administrative-level flow data between overnight locations in Kenya and Namibia derived from CDRs: where the model spatial resolution exceeds that of the mobility data, we compare the flow data between a particular origin and destination with the sum of all model flows between cells that lie within those particular origin and destination administrative units. Clear evidence of over-dispersion supports the use of negative binomial instead of Poisson likelihood for count data with high values. Radiation models use fewer parameters than the gravity model and better predict trips between overnight locations for both considered countries. Results show that estimates for some parameters change between countries and with spatial resolution and highlight how imperfect flow data and spatial population distribution can influence model fit.

Highlights

  • Over the past few years, individual-based models have been widely adopted across multiple scientific disciplines [1,2,3,4,5,6,7,8]

  • Population distribution data are freely available from LandScan

  • Spatial data on administrative units are freely available from GADM

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Summary

Introduction

Over the past few years, individual-based models have been widely adopted across multiple scientific disciplines [1,2,3,4,5,6,7,8] Such models simulate population processes providing a set of rules that determine the behaviour of individuals in the population depending on their state and on the interactions they have with other individuals in the model. Typical data sources include census data on migration and commuting, satellite imagery, surveys, airline and other long-distance travel ticketing records [9,10,11] Each of these sources provides travel data at different spatio-temporal resolutions and has specific sampling biases; they inform mobility models in a wide variety of fields [12], including epidemiological modelling [13,14,15,16]

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