Abstract
(2-trans-Hydroxycyclopropyl)trimethylammonium iodide (4) may be obtained by cleavage of the trans-benzyl ether (7) with concentrated aqueous hydrogen iodide. Under the same conditions the corresponding cis-benzyl ether (8) also gives the trans-cyclo-propanol derivative (4). For the course of the reaction, an SN2-type mechanism with inversion of configuration at the cyclopropane carbon is proposed.
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