Depth imaging through the anterior to posterior segment of the whole human eye based on optical coherence tomography in the spectral-domain

Abstract

An optical coherence tomography system is proposed for synchronized zoom imaging of the cornea, retina, and the whole eye. The system was combined with an electrically tunable lens provided with 15 ms zoom response time and a customized optical delay line. A full-range technique was used to extend the depth of the B-scan cross sectional image. The anterior and posterior segments of the human eye were scanned by a coaxial rotating double galvanometer system. The transverse scanning ranges can reach up to 8 mm in whole eye scanning and 14 mm in fast single-frame scanning. The speed of image acquisition is over 4 Hz, and five B-scans were stitched to obtain a whole eye image. The system with electrically tunable lens and optical delay line achieved whole eye depth imaging in vivo.