Abstract
AbstractA simple and efficient synthesis of a solid‐supported thiol has been developed. Mercaptoacetic acid was first protected by the dimethoxytrityl group and then anchored to Wang resin through an ester bond. Deprotection of the thiol function led to resin‐supported mercaptoacetic acid, a useful supported thiol reagent that can be used in the polymer‐assisted solution‐phase removal of nosyl (Ns) groups from the amino function of α‐amino acids in peptide synthesis. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
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