Depression,anxiety and their effects on quality of life before metabolic surgery in obese patients

Abstract

Objective To investigate the status of depression/anxiety in obese patients seeking metabolic surgery and analyze the effects of depression/anxiety on different aspects of quality of life. Methods Convenient sampling was used and 117 metabolic surgery were recruited from the Department of Bariatric and Metabolic Surgery in the First Affiliated Hospital of Nanjing Medical University from March to July,2017. Patient Health Questionnaire(PHQ-9),Generalized Anxiety Disorder 7-item scale(GAD-7), 12 item Short-Form Health Survey (SF-12) and the general information and disease characteristics questionnaire were used to collect data. Results Nearly 25.6%(30/117) of the patients suffered from moderate, moderately severe and severe depression symptoms and the median and interquartile range of PHQ-9 was 6 and 7 points. 16.2% (19/117) of the patients had moderate and severe anxiety symptoms and the median and interquartile range of GAD-7 was 3 and 6 points. Multiple linear regression analysis showed that scores in the physical component of the SF-12 were associated with the body mass index, the presence of comorbidities and depression,which could explain 20.0% of the total variance; the symptoms of depression and anxiety were negatively related to the mental component summary of SF-12, which could explain 49.6% of the total variance. Conclusions The present findings suggests that there is a high occurrence of depression and anxiety in metabolic surgery patients, which severely impair the patients′ quality of life. As for the obese patients seeking metabolic surgery for treatment, routine screening of depression and anxiety incorporating the diagnosis of the problems are warranted. Then intervention based on the assessment can be exerted to maximize the benefit of patients undergoing the surgery in the long term. Key words: Anxiety; Depression; Quality of life; Metabolic surgery