Abstract
Seven conscious chronically cannulated ewes and their fetuses were studied in the third trimester of pregnancy. Compression of the umbilical cord for 4 min, to a degree simulating the occurrence in clinical obstetrics, not only produced the expected fetal hypoxia, acidemia, and cardiovascular effects but also significantly reduced uterine blood flow. In a ewe with twin fetuses, compression of the cord to only one fetus decreased the flow to that horn and had no effect on flow to the other horn. It is postulated that the reduction in uteroplacental flow was due to stimulation of alpha-adrenoceptors in the maternal placental vasculature by catecholamines of fetal organ, or the effects of increased tissue-fluid pressure in the fetal placenta, or a combination of these mechanisms.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
