Abstract

SummaryThe widespread use of microwave equipment presents potential hazards to health from inadvertent exposure. The hazards due to the heating effect of microwaves are well recognized. Recent evidence suggests that microwave radiation produces other biological effects that are not in any way due to heating. Experiments were performed to investigate the non-thermal effects of microwaves on the process of phagocytosis. Monolayer cultures of mouse macrophages on cover-slips were perfused with suspensions of human red blood cells while being exposed to microwave radiation of 2450 MHz frequency, at a power level of 50 mW/cm2, under strict temperature control. Comparison of the phagocytic indices of the irradiated cultures with unirradiated control cultures demonstrated a marked depression of phagocytic activity. Further investigation showed that macrophage phagocytic activity was restored to normal if the radiation was discontinued. The potential hazards to health of this phenomenon are briefly discussed.

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