Depression in the nursing home: a cluster-randomized stepped-wedge study to probe the effectiveness of a novel case management approach to improve treatment (the DAVOS project)

Valentina A Tesky,Arthur Schall,Johannes Pantel,Ulrike Schulze,Monika Knopf,Frank Oswald,Jochem König,Elisabeth Arens,Maria Blettner,Ulrich Stangier

doi:10.1186/s13063-019-3534-x

Abstract

BackgroundDepression is the second most common psychiatric illness in old people. Up to 30% of nursing home residents have minor or major depression. Although depressive disorders in old age can be improved and even cured with adequate therapy, they often go unnoticed in nursing home residents and remain untreated. This highlights a striking deficit in health care and might result not only in lower quality of life among those concerned but also in poor physical functioning, premature mortality, and increased hospitalization rates.MethodsThe aims of the interdisciplinary research project DAVOS are to implement an innovative and stepped structural case management program to improve depression treatment for nursing home residents by a modularized intervention and to assess it in terms of its effectiveness. Intervention modules are in line with recommendations given by the German national treatment guidelines for depression (S3 guidelines). Ten nursing homes in Frankfurt, Germany, will participate in the project, which aims to recruit a study population of 380. The recruitment will continue throughout the trial (open cohort). Persons (>60 years) who live in a nursing home, have no medical diagnosis of dementia, and can provide their informed consent to participate are eligible for inclusion in the study. Residents with a clinical diagnosis of dementia, alcohol or substance-related disorders, or other serious psychiatric illnesses will be excluded. DAVOS is a controlled cluster-randomized study that employs a stepped-wedge design.DiscussionOur main hypothesis is that the implementation of the intervention will lead to a decline in the prevalence of depression and a reduction in depression symptoms among the home residents. In addition, we expect the intervention to have a positive impact on secondary outcomes such as level of functioning, quality of life, and social participation. The project’s results can make an important contribution toward improving the health care of nursing home residents who have late-life depression.Trial registrationDRKS, DRKS00015686, Oct. 10, 2018.

Highlights

Depression is the second most common psychiatric illness in old people
As a result of the structural peculiarities of the German health-care system, major depression is diagnosed in a mere 42.9% of nursing home residents who have the disease and only half of them receive an appropriate therapy [5]. This highlights a striking deficit in health care and results in lower quality of life among those concerned and in poor physical functioning, premature mortality, and increased hospitalization [6–8]
Previous results show that the implementation of Act in Case of Depression” (AiD) in Dutch nursing homes led to a significant decline in the prevalence of depression and an improvement in quality of life among residents [34–36]

Summary

Introduction

Depression is the second most common psychiatric illness in old people. Up to 30% of nursing home residents have minor or major depression. Depressive disorders in old age can be improved and even cured with adequate therapy, they often go unnoticed in nursing home residents and remain untreated This highlights a striking deficit in health care and might result in lower quality of life among those concerned and in poor physical functioning, premature mortality, and increased hospitalization rates. As a result of the structural peculiarities of the German health-care system, major depression is diagnosed in a mere 42.9% of nursing home residents who have the disease and only half of them receive an appropriate therapy [5] This highlights a striking deficit in health care and results in lower quality of life among those concerned and in poor physical functioning, premature mortality, and increased hospitalization [6–8]. The existence of chronic untreated depression has been shown to have a negative influence on the course of numerous somatic diseases as well as the risk of polypharmacy [9]

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