Abstract

According to the World Health Organization (WHO), chronic diseases are the leading cause of death and disability worldwide and estimated to contribute to 73% of all deaths by 2020. In addition to the difficulty in effectively managing chronic diseases, they are often complicated further by the co-morbid depression stemming from the original disease. Depression has the highest burden of disease affecting more than 264 million people worldwide and worsens the burden of co-existing chronic medical diseases as well. A bidirectional relation exists between depression and chronic medical diseases. Statistical mapping of chronically ill patients of Pakistan suggests that 50% of its population suffers from some form of chronic disease. Little data exists for the prevalence of depression in chronically ill patients from most of Pakistan.Our objectives were to observe the patterns of depression in chronically ill patients and outline the need for intervention (if any) on a population of Railway General Hospital (RGH - a tertiary healthcare hospital in Rawalpindi, Pakistan). We also aimed at finding out the relation (if any) of age, gender, number of hospital admissions, education and effectiveness of medical disease management with depression. A cross sectional study was conducted on patients admitted due to their chronic medical diseases out of a population of 11,000 presenting at the medical OPD of RGH over a period of three months using Patient Health Questionnaire-9 (PHQ -9) Urdu version. About 50% of the patients suffered from moderate to severe forms of depression. A significant positive correlation was found between age and past psychiatric history of illnesses other than depression with depression while no significance was found with number of hospital admissions, gender or education level; 35% had suicidal ideation.Depression is quite often dismissed, underdiagnosed and leads to a poor quality of life and decrease in cost effectiveness in our population. Pakistan needs to use more resources on managing depression and medical professionals need to change their attitudes in holistically managing the patients. Treating depression is just as important as managing other symptoms of chronic medical diseases.

Highlights

  • According to the international classification of diseases (ICD-10), depression is characterized as a mood disorder [1]

  • The statistical analysis of a hundred patients revealed that 24% were admitted due to uncontrolled diabetes and its complications, 19% due to the exacerbations of chronic obstructive pulmonary disease (COPD), 14% for complications of coronary artery disease (CAD), 8% for the management of chronic liver disease, 9% due to uncontrolled hypertension and debilitating rheumatoid arthritis each, 8% suffering from complications of chronic kidney disease, 5% due to underlying thyroid disease and a 4% for the management of chronic iron deficiency

  • By using PHQ-9 on the aforementioned patients, we found that the patients with COPD suffered the most at 73.68% (n=14) affected with moderate to severe depression

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Summary

Introduction

According to the international classification of diseases (ICD-10), depression is characterized as a mood disorder [1]. Mood is a predisposition characterized by chronic chemical changes in the brain that influence neuronal growth and may be referred to as a chronic emotional state [2]. Emotions are acute reactions, states and responses to stimuli that are often influenced by temperamental states [2]. While sadness is an emotion, depression is a mood disorder characterized by persistent sadness, low energy, decreased interest in daily activities, decreased pleasure, feelings of guilt and suicidal ideation over a period of at least two weeks, often accompanied by changes in sleep and appetite [1]. It has been shown to significantly increase suicide rate and worsen chronic medical diseases [4]

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