Abstract

BackgroundDepression is a common co-morbid, disabling disorder that affects 10–25% of cancer patients. It causes substantial functional impairment and lowers survival rate of breast cancer patients. Therefore, the aim of this study is to determine the magnitude of depression and its association with social support among breast cancer patients in Addis Ababa, Ethiopia.MethodsA cross-sectional study which included 428 breast cancer patients was conducted in seven health facilities in Addis Ababa, Ethiopia. Depression and Social Support were assessed using standard tools Patient Health Questionnaire 9 (PHQ 9) and Multidimensional Scale of Perceived Social Support (MSPSS) respectively. Descriptive statistics were done based on the standard PHQ9 cut off points (0–4, 5–9, 10–14, 15–19 and ≥ 20). Mann-Whitney and Kruskal Wallis tests were employed to compare MSPSS score among depressed and non-depressed patients and across the different levels of depression. Bivariate and multivariate logistic regression was done to identify factors associated with depression.ResultThe prevalence of depression among breast cancer patients was 25% (107/428), andaccording to the PHQ9 score categorization, 70/428 (16.4%), 30/428 (7.01%) and 7/428 (1.64%) of these patients were having moderate, moderately severe and severe depression respectively. Age, occupation, type of health facility treated, severity of pain, hormonal therapy and having problem with employer/ family were significantly associated with depression. The participants’ MSPSS total score was overall found to be high (70.35 ± 16.81). Those women who had moderate and severe depression had lower mean MSPSS scores compared to women with none/ minimal depression (P = 0.002).ConclusionThis study found that one in four breast cancer patients had depression. Depression is associated with poor social support given by family, friends and significant others. Therefore, screening for depression and psychosocial service should be integrated in the routine breast cancer care in Ethiopia.

Highlights

  • Depression is a common co-morbid, disabling disorder that affects 10–25% of cancer patients

  • Depression is associated with poor social support given by family, friends and significant others

  • Screening for depression and psychosocial service should be integrated in the routine breast cancer care in Ethiopia

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Summary

Introduction

Depression is a common co-morbid, disabling disorder that affects 10–25% of cancer patients It causes substantial functional impairment and lowers survival rate of breast cancer patients. Breast cancer is one of the leading cancers in developing countries with an estimated 882,900 new cases and more than 324,300 deaths each year. According to the World Health Organization (WHO) country profile report in 2018, breast cancer is the leading cancer in Ethiopia with an estimated 15, 244 (22.6%) new cases and 5 years prevalence of 46.7%. Several epidemiological studies revealed that depression is very common among breast cancer patients which is associated with substantial functional impairment and diminished survival [10]. According to reports from various studies, the prevalence of depression among breast cancer patients ranged from 9.3 to 56% [10,11,12,13,14]. A recently conducted systematic review which included several studies all over the world reported that the prevalence of depression among breast cancer patients is 32.2% [15]

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