Abstract
Introduction. Little is known about the roles that lifetime psychiatric disorders play in psychiatric and vocational outcomes of aneurysmal subarachnoid haemorrhage (SAH).Materials and methods. Eighty-three SAH patients without apparent cognitive dysfunction were assessed using the Structured Clinical Interview for DSM-IV axis I disorders (SCID-I) after their SAH. Diagnoses were assessed for three time periods, ‘lifetime before SAH’, ‘12 months before SAH’ and ‘7 months after SAH’.Results. Forty-five percentage of patients with SAH reported at least one lifetime psychiatric disorder. After SAH, symptoms of depression and/or post-traumatic stress disorder (PTSD) were seen in 41%, more often in those with a psychiatric history prior to SAH (p = 0.001). In logistic regressions, depression after SAH was associated with a lifetime history of major depression, or of anxiety or substance use disorder, as well as with lifetime psychiatric comorbidity. Subsyndromal or full PTSD was predicted by a lifetime history of major depression. After the SAH, 18 patients (22%) had received psychotropic medication and/or psychological treatment, 13 of whom had a disorder. Those with a lifetime history of major depression or treatment with antidepressants before SAH had lower return to work rates than others (p = 0.019 and p = 0.031, respectively). This was also true for those with symptoms of depression and/or PTSD, or with antidepressant treatment after SAH (p = 0.001 and p = 0.031, respectively).Conclusions. Depression and PTSD are present in a substantial proportion of patients 7 months after SAH. Those with a history of psychiatric morbidity, any time before the SAH, are more at risk and also constitute a risk group for difficulties in returning to work.
Highlights
Little is known about the roles that lifetime psychiatric disorders play in psychiatric and vocational outcomes of aneurysmal subarachnoid haemorrhage (SAH)
A number of studies suggest that patients afflicted with subarachnoid haemorrhage (SAH) have a considerable burden of psychopathology in its aftermath, such as depression and post-traumatic stress disorder (PTSD)
Of the 325 patients with SAH who were admitted during the study period, 129 met criteria for inclusion (Fig. 1)
Summary
Little is known about the roles that lifetime psychiatric disorders play in psychiatric and vocational outcomes of aneurysmal subarachnoid haemorrhage (SAH). After the SAH, 18 patients (22%) had received psychotropic medication and/or psychological treatment, 13 of whom had a disorder Those with a lifetime history of major depression or treatment with antidepressants before SAH had lower return to work rates than others (p 1⁄4 0.019 and p 1⁄4 0.031, respectively). This was true for those with symptoms of depression and/or PTSD, or with antidepressant treatment after SAH (p 1⁄4 0.001 and p 1⁄4 0.031, respectively). Depression and PTSD are present in a substantial proportion of patients 7 months after SAH Those with a history of psychiatric morbidity, any time before the SAH, are more at risk and constitute a risk group for difficulties in returning to work. Prevalence figures for PTSD after SAH show even greater variation, with studies reporting from 6%,6 19%,11 32%,12 to 60%.8
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