Abstract
Abstract Depression and diabetes mellitus are two chronic disorders, and both of which have occupied places in the WHO top 10 causes of global burden of diseases. These two disorders have more in common than what was previously thought. Several hypotheses involving biology, genetics and psychology have attempted to explain the link between the two, but it has proven to be elusive until now. Theories involving vascular factors, insulin and glucose metabolism, neurological changes and lifestyle aberrations have come close to forming a unitary explanation for this disease model. The understanding into the shared pathogenesis of depression as well as diabetes has opened up new frontiers into research of chronic disorders and how closely they interact with each other. This review attempts to break the descartian dichotomy between mind and body by highlighting the strong link between depression and diabetes.
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