Abstract
To increase the sensitivity of strains of salmonellas used for prel iminary screening of mutagens (potential carcinogens) the use of plasmid pKlVI101 has been suggested [9]. The mechanisms lying at the basis of the action of plasmids on bacterial mutability is not yet known, so that the desirabiiity of their use for assessment of agents dangerous to man is questionable [5]. Data showing that plasmid pKM101 can endow salmonellas with the capacity for induced mutagenesis are particularly interesting. This conclusion was reached from experiments with UV light, which is known to act as a carcinogen [8] but, in the absence of plasmids, does not induce mutations in salmonellas [2].
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
